Standardized microarray data analysis workflow.

Abstract

<p>Starting from the publicly available EMBL repository ArrayExpress: 1) Relevant prostate cancer studies were selected and downloaded; 2) Quality control and data pre-processing steps were performed in the R environment. Microarrays with insufficient sample quality, hybridization quality, signal comparability or array correlation were excluded; 3) For each included study, statistical analysis was performed and pathway analysis was run with PathVisio to identify the biological processes involved; 4) Results were then integrated and compared to literature findings.</p