Effect of selected miRNAs on the expression of endogenous <i>ACVR1/Alk-2</i> mRNA.

Abstract

<p>Selected miRs were transfected in the indicated cell lines and expression of <i>ACVR1/Alk-2</i> mRNA was measured by RT-qPCR and compared to the expression level of <i>ACVR1/Alk-2</i> transcript from cells transfected with a negative scrambled pre-miR control considered as 100. (<b>A</b>) miR148b; (<b>B</b>) miR365; (<b>C</b>) miR26a. Differences between the effect on <i>ACVR1/Alk-2</i> mRNA of specific miR compared to that of the Cy3-labeled negative control were evaluated by performing a <i>Student’s t-test</i> with <i>p</i><0.05*, <i>p</i><0.01**, <i>p</i><0.001***.</p