Dose-dependent inhibition of alanine mutants by anti-SR-BI and silencing of SR-BI.

Abstract

<p>Huh-7.5 cells were infected with Luc-Jc1 WT or with the indicated E2 mutant viruses as follows: (A and B): in the presence of anti-SR-BI antibodies at the given concentrations. (C) Huh-7.5 cells were transfected 48 h prior to infection with control (scrambled) or SR-BI-specific siRNAs. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052651#s3" target="_blank">Results</a> are drawn from a representative experiment of three independent experiments. All points represent the mean of duplicate infections measured in duplicate (n = 4, ± SD).</p