Dose-dependent inhibition of alanine mutants by conformational anti-E2 AR3A antibodies and patient-derived IgG.

Abstract

<p>Huh-7.5 cells were infected with Luc-Jc1 WT or with the indicated E2 mutant viruses as follows: viruses were with pre-incubated with anti-E2 AR3A antibodies (A & B) or patient-derived IgG (C & D), at the given concentrations. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052651#s3" target="_blank">Results</a> are drawn from a representative experiment of three independent experiments. All points represent the mean of duplicate infections measured in duplicate (n = 4, ± SD).</p