Immunohistochemical analysis of the peripheral and central portions of control (FTH-BCSC) and docetaxel-treated (FTH-BCSC Doc) xenograft tumors.

Abstract

<p>(A) Double staining for CD44 and CD24 expression performed in FTH-BCSC and FTH-BCSC Doc tumors (x400; bar, 100 µm). (B) The percentage of CD44+/CD24−, CD44+/CD24+, CD44−/CD24+, CD44−/CD24− and EGFP-positive cells in the periphery and center of the FTH-BCSC and FTH-BCSC Doc tumors. *<i>P</i><0.05. (C) Cell proliferation marker (phospho-histone 3, PH3) expression in the FTH-BCSC and FTH-BCSC Doc tumors (x200; bar, 100 µm). (D) The percentage of PH3-positive/EGFP-positive cells in the periphery and center of the FTH-BCSC and FTH-BCSC Doc tumors. **<i>P</i><0.01.</p