The flow chart of the rsFC pattern classification obtained by applying MVPA to the sample dataset in the slow-5 frequency band.

Abstract

<p>The sample dataset was a 39-by-4005 matrix in this study and was comprised of 4005 features, that is, inter-regional functional connections. Each row and each column of the sample dataset represented a subject and a feature, respectively. Recursive feature elimination (RFE) was applied to the sample dataset for feature selection and to calculate the rank of the feature weight (a row vector). The subsets of the sample dataset were produced according to the feature weighting rank. The classifier was used to separate the VaD brains from those of the controls in each subset of the sample dataset by using a leave one-out-subject-cross-validation (LOOCV). The accuracy rate was used to compare the discriminative information in each subset of the sample dataset.</p

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