Abstract

<p>(A) Ultrasound analysis showing an open <i>Tyr::Cre; ctnnb1Δex3</i>/+ (ctnnb1Δex3) DA. (B) Enlargement of (A) showing the DA. (C) Ultrasound analysis of a ctnnb1Δex3 patent foramen ovale. (D) Shunting through the foramen ovale as observed by echo Doppler analysis in ctnnb1Δex3 mice. (E) The foramen ovale remains open in ctnnb1Δex3 hearts. Note the presence of pigmented cells. LA: left atrium, RA: right atrium, Ao: aorta, RVOT: right ventricle outflow tract, DA: ductus arteriosus.</p

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