Craniofacial development in wild type and <i>Scube3^−/−</i> mice.

Abstract

<p>Histological comparison of the developing craniofacial region in wild type and <i>Scube3^−/−</i> mice at E13.5 and E15.5. (A–C) E13.5 wild type; (D–F) E13.5 mutant; (G–I) E15.5 wild type; (J–L) E15.5 mutant. All sections are orientated in the frontal plane and stained with Haematoxylin and Eosin. Orientation is through the primary palate (left panels), central region (middle panels) and posterior region (right panels) of the secondary palate. mdi, mandibular incisor tooth germs; mdm, mandibular molar tooth germs; mxi, maxillary incisor tooth germs; mxm, maxillary molar tooth germs; nc, nasal cavity; ns, nasal septum; ps, palatal shelf; t, tongue; vi, vibrissae; vno, vomeronasal organ.</p