Effects of Berberine on the phosphorylation of AMPK-Thr 172 and ACC-Ser79, AMP/ATP ratios, and superoxide production in BAEC.

Abstract

<p><i>A & B</i>, Dose-dependent increase of of AMPK-Thr172 and Ser79 phosphorylation by berberine in BAEC. Confluent BAEC were incubated with different doses of Berberine (1 µM to 200 µM) for 2 h. The blot is representative of three individual experiments. n = 3 *<i>p</i><0.05, control versus Berberine-treated. <i>C & D</i>, Time-dependent increase of AMP-Thr172 and Ser79 by Berberine (10 µM) in BAEC. The blot is representative of three blots obtained from three separate experiments. n = 3 * <i>p</i><0.05, control versus Berberine-treated.</p