<p>(A) IFN-γ; (B) IL-2. Supernatants were collected at 48h after HBV S and PreS1 peptide pool stimulation and cytokines were quantified by ELISA. IFN-γand IL-2 were detected and data were shown as means±SEMs. Statistical differences between groups were determined, and differences are shown as *p<0.05 and **p<0.01. SS1: HBSS1 A, alum; C, CpG; P, poly(I:C). Adjs: control group with adjuvants mixture.</p