Microscopic characterization of keratinocyte-specific NRP1-deficient mice.

Abstract

<p>Hematoxylin/eosin staining shows no differences in skin architecture between control and NRP1-deficient mice postnatally or in adult mice. Likewise, no changes in the expression of various differentiation markers could be detected. These markers included keratin 14 for basal keratinocytes, keratin 10 for suprabasal keratinocytes and loricrin for late stage differentiation, preferentially in the granular layer.</p