Effect of muscle contractions on interstitial ATP of perfused muscle with or without inhibitors.

Abstract

<p>Blood-perfused rat gastrocnemius muscle was subjected to repeated muscle contractions at 1 Hz in the absence of inhibitors (A) or in the presence of CFTR_inh-172 (20 µM; B), KT5720 (10 µM; C), amiloride (100 µM; D) or SN-6 (20 µM; E). Values are the mean ± SEM of 6 (A), 11 (B), 7 (C), 8 (D) or 5 (E) tests. *, significant difference between rest and contractions; #, significant difference between absence and presence of inhibitor (1-way repeated measures ANOVA followed by the Bonferroni post-hoc t-test).</p