Anti-angiogenic effects of SU5416 and VRI in zebrafish.

Abstract

<p>One dpf Tg<i>(fli-1:EGFP)</i> transgenic zebrafish embryos were treated with SU5416, VRI or DMSO (vehicle control) at the indicated concentrations for 2 days. After treatment, intersegmental-vessel formations were observed under fluorescence microscopy. Deficit of blood vessels was indicated by yellow asterisks.</p