<p>Note: Mice were randomly assigned to five groups (8/group). Except for the NS and RVJ mock groups, mice received different prime–boost vaccination regimens. Sera were collected 2 weeks after each immunization, and HBV specific antibody was detected by ELISA. Seroconversion is indicated in the table.</p><p>NS: Normal saline.</p><p>RVJ: recombinant vaccinia virus.</p