Dark-adapted 10-Hz flicker ERG response amplitude-intensity profiles in <i>C57BL/6</i>, <i>cpfl1</i> and <i>rho^−/−</i> mice.

Abstract

<p>There are two peaks in the wild-type mice, with the first representing rod-driven and the second representing cone-driven responses (Panel A). In <i>cpfl1</i> (n = 5) mice, the rod peak still exists while the cone peak is absent. In <i>rho^−/−</i> (n = 4) mice the rod peak is absent, but the cone peak persists. The summation of the amplitude-intensity curves of the flicker ERG responses in <i>rho^−/−</i> and <i>cpfl1</i> mice mimics the profile of the <i>C57BL/6</i> (n = 5) mice. (Panel B. Bars indicate the standard deviation.).</p