Correlation between the durations of immobility in the forced swim test and levels of cytokines and monoamines (B, C).

Abstract

<p>Correlations in immobility are shown in the scatter-plat with IL-6 and TNF-á (<i>Closed circles = </i>IL-6: <i>closed triangles = </i>TNF-á) (A), 5-HT and 5-HIAA (<i>Closed circles = </i>5-HT : <i>closed triangles = </i>5-HIAA) (B) and DA and DOPAC (<i>Closed circles = </i>DA : <i>closed triangles = </i>DOPAC) (C) plotted separately. Data were analyzed using Pearson’s correlation coefficients (2-tailed).There were significant correlation at the level of 0.05 between the stress condition and changes in cytokines (IL-6, r = 0.48 and TNF-á, r = 0.46) and monoamines (5-HT, r = −0.46; 5-HIAA, r = −0.46; DA, r = −0.47) concentrations.</p