Quercetin and allopurinol regulate renal mRNA levels of lipid metabolism-related genes in streptozotocin (STZ)-treated rats.

Abstract

<p>Graphic presentation of renal mRNA levels by real-time PCR analysis of rPPAR-α (A), rCPT1 (B), rACC2 (C) and rOCTN2 (D) at 7 weeks after STZ injection in different groups of rats as indicated. The relative mRNA levels were determined after normalization with rGAPDH. The data are expressed as the means ± SEM (n = 3–4). ⁺⁺⁺<i>P</i><0.001 <i>versus</i> normal control; *<i>P</i><0.05, **<i>P</i><0.01, ***<i>P</i><0.001 <i>versus</i> STZ control.</p