The 3-D QSAR/CoMFA analysis showing the correlation between the experimentally-determined COX-stimulating activity values and the predicted values.


<p>Nine representative bioflavonoids plus flavone were used in the analysis. The experimental values were based on measuring PGE<sub>2</sub> production, which was determined in our previous study <a href="" target="_blank">[15]</a>. Statistical parameters (<i>q</i><sup>2</sup>, <i>r</i><sup>2</sup>, PC, SEE, and F) for the CoMFA models of COX I and II are also listed in the figure.</p

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