<p>A. Time-of-drug-addition assay indicated that LSA blocked HIV-1 infection at an entry stage. B. MT-2-CHO-WT Cell-cell fusion was inhibited in the presence of LSA. C. LSA, not LA blocked sCD4 binding to rgp120s from ADA and IIIB strains. D. LSA inhibited JR-FL and HXB2 HIV-1 virion attachment to Ghost (3) X4/Hi5 and HEC-1-A cells. Heparan sulfate (100 μg/ml) was used as a control. Data shown were the average of three independent experiments. Error bars denoted standard errors of the mean values.</p
