Increased susceptibility to Aβ42-mediated cell death in LRP1 minireceptor-expressing cells.

Abstract

<p>N2a-pcDNA3 and N2a-mLRP4 cells were incubated with increasing concentrations of Aβ42 for 24, 48 and 72 h and cell viability was assessed by the reduction of the MTS dye. Decreased viability was detected only after 72 h incubation with a high concentration of Aβ42 in LRP1 minireceptor expressing cells. * p<0.05, <i>t</i>-test. n = 3.</p