<p>(A) Bleeding time of WT and C3−/− mice exposed to normoxia or CH (n = 5–7). (B) Scatter plot showing platelet population in platelet rich plasma. All experiments were similarly gated to the area encircled. (C) Flow cytometry histogram demonstrating that the gated cell population is positive for the platelet marker CD41. (D–E) Representative flow cytometry histograms of platelets from (D) hypoxic WT or (E) hypoxic C3−/− mice stained with P-selectin antibody or isotype control. (F) Percent P-selectin positive platelets in PRP isolated from normoxic and hypoxic WT or C3−/− mice (n = 6). Bars represent mean ± SD. *<i>P</i><0.05; n.s. = not significant.</p
