Markers of Inflammation and endothelial dysfunction in WT vs. C3 −/− mice.

Abstract

<p>(A) IL-6 mRNA was measured by quantitative rtPCR in RNA prepared from normoxic or hypoxic WT and C3−/− lungs. IL-6 levels were normalized to the house keeping gene β2-microglobulin. (B) ICAM-1 was quantified by ELISA in lung homogenates from normoxic or hypoxic WT or C3−/− mice. (C) ET-1 was quantified by ELISA in plasma from normoxic or hypoxic WT or C3−/− mice. Bars represent mean ± SD (n = 4) for A–C. *<i>P</i><0.05.</p