Proliferation, apoptosis and migration of CXCR7-positive SW480 and Colo 205 cell lines incubated with LPS.

Abstract

<p>A, Incubation with LPS, SW480 cell line pretreated with AMD3100 (10 µg/ml) proliferated significantly in response to CXCL12 (100 ng/ml; 48 h), Colo 205 cell line also proliferated significantly in response to CXCL12. B, CXCL12 activation of its receptor CXCR7 did not exert an antiapoptotic effect. C, Pretreatment with AMD3100, SW480 cell line migrated significantly more in response to CXCL12 after 24 h of incubation with LPS, Colo 205 cell line also migrated significantly in response to CXCL12.</p