Effect of mitochondrial substrates on mechanism of maintenance of Δψ<sub>m</sub> in human fibroblast with PINK1 mutations.

Abstract

<p>Application of pyruvate (5 mM) or/and methyl succinate (5 mM) to fibroblasts increased Δψ<sub>m</sub>; Substrate provision prevented the oligomycin induced mitochondrial depolarisation in L2123, L2124 and L1703 fibroblasts.</p

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