JDP2 binding to the GR DBD fails to induce any significant structural changes in DBD.

Abstract

<p>A) Far-UV CD spectra of recombinant DBD (a.a. 398–500), JDP2, and DBD:JDP2 mixture. B) Far-UV CD spectra of DBD:JDP2 mixture (experimental), and additive of DBD+JDP2 (theoretical sum of DBD plus JDP2). Each spectrum presented is the average of five spectra recorded, corrected for the contribution of the buffer, and smoothed. C) Far-UV CD spectra of recombinant AF1 (a.a. 77–262), JDP2, and AF1:JDP2 mixture. D) Far-UV CD spectra of AF1:JDP2 mixture (experimental), and additive of AF1+JDP2 (theoretical sum of AF1 plus JDP2). Each spectrum presented is the average of five spectra recorded, corrected for the contribution of the buffer, and smoothed.</p