<p><b>(A)</b> BA4 reactivity was measured by competitive ELISA in aortic extracts from patients with MFS (n = 6), isolated TAA (n = 8) and controls (n = 11). A statistically significant increase in BA4 reactivity as compared to control samples was observed for the samples from individuals with MFS and isolated TAA. <b>(B)</b> Chemotactic activity of the same extracts was measured by a Boyden chamber. A statistically significant increase in chemotactic activity as compared to control samples was observed for the samples from individuals with MFS and isolated TAA. Red lines indicate the median levels of BA4 reactivity or chemotactic index (CI). Data are representative of three independent experiments. * 0.05, **0.01.</p
