GRP94 deficiency led to increased granulocyte–monocyte progenitors in the bone marrow.

Abstract

<p>A) Quantitation of flow cytometric analysis of myeloid and lymphoid progenitors including common myeloid progenitor (CMP), granulocyte-monocyte progenitor (GMP), megakaryocyte-erythroid progenitor (MEP) and common lymphoid progenitor (CLP) from WT (n≥7) and cKO (n≥10) mice. B) Quantitation of colonies formed from unfractioned BM from WT (n = 4) and cKO (n = 7) mice in methylcellulose medium. All data are presented as mean ± s.e., *p<0.05, **p<0.01.</p