Summary of EBA-175 RII specific mAbs.

Abstract

<p>ND: not determined</p><p>NA: not achievable. R216 at 333 and 666 µg/ml IgG blocked EBA-175 binding by 14 and 21%, respectively.</p><p># <i>P. falciparum</i> FVO 2 cycle suspension growth inhibition assay (GIA).</p>1<p>mAbs compete against each other for binding RII by competition ELISA.</p><p>c: constrained epitope; L: linear epitope; immppt: immunoprecipitate.</p><p>*incomplete reduction; ** partial denaturation/reduction.</p