Effect of IL-17A, IL-17F or IL-22 on transepithelial diffusion rate of FITC-dextran in ARPE-19 monolayer.

Abstract

<p>Stimulation of ARPE-19 monolayer with 50 ng/ml IL-17A, IL-17F or IL-22 for 6 days induced a higher FITC-dextran diffusion rate at 24 hours compared with the control group. A diffusion percentage approaching 100% indicates that the amount of dextran-FITC in the upper and lower chamber approaches the same values. IL-22 had no effect on diffusion rate. Data were shown as the means±SEM of four independent experiments. *<i>p</i><0.05 versus the control group.</p