Effect of IL-17A, IL-17F or IL-22 on TER of cultured ARPE-19 monolayer.

Abstract

<p>Monolayers were cultured for 21 days, where after the various stimuli were added. Incubation of ARPE-19 monolayers with 50 ng/ml IL-17A or IL-17F induced a gradual decrease of TER, and a significant effect occurred 5 days (p = 0.019, p = 0.045) after stimulation. The continuous decreases were also observed 6 days (p = 0.01, p = 0.016) and 7 days (p = 0.023, p = 0.008) after stimulation. IL-22 had no effect on TER. Data were shown as the means±SEM of four independent experiments. *<i>p</i><0.05 versus the control group.</p

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