Tables S1, S2, S3, S4, S5 and S6. Table S1. This table provides: a) Gene-specific assay information including SNP sites, primer and internal standard sequences, b) Subject-specific demographic information, and c) assay- and subject-specific transcript abundance values (target gene molecules/106 ACTB molecules). Table S2. Population used for allele specific expression analysis: Summary demographic characteristics of the study population of allele specific expression (subject total n = 180). Table S3. Transcription factor-target inter-gene correlation in Control, COPD, or All subjects (p-value < 0.05). Table S4. Analysis of covariance (ANCOVA). Gene expression values (Independent Variables) significantly correlated (positively or negatively) with COPD subjects (Dependent Variable) after control for expression values of other genes (Covariates). Table S5. ERCC5 SNPs linked to rs17655 and rs873601 (D > 0.95) and with p < 0.05 in LHS and COPDgene NHW CB cohorts. COPD GWAS p-values, population-specific genotype frequencies, and epigenetic annotation information from Haploreg/Encode. Table S6. Haplotype structure between COPDgene NHW1 associated SNP rs4150275, putative functional cis-rSNP rs873601, and DAE2 SNP rs17655. (XLSX 109 kb