Comparison of the activation of truncated forms of PTPRZ1 luciferase reporter by HIF-1α and HIF-2α and their degradation-resistant forms.

Abstract

<p>(A) Hep3B or (B) HEK293T cells were co-transfected with 300 ng of each PTPRZ1 promoter and 50 ng of an internal β-gal control plasmid in the presence of 250 ng of an expression plasmid encoding HIF-1α, drHIF-1α, HIF-2α, drHIF-2α, or pcDNA3.1control. Results are expressed as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009641#pone-0009641-g002" target="_blank">Figure 2</a>.</p