PLN activates HEK cells via TLR4.

Abstract

<p>IL-8 production in HEK-293 cells transfected with CD14 and either TLR2 or TLR4 were incubated with medium (control), LPS (100 ng/ml), LTA (5 µg/ml) or PLN (1 µg/ml) for 6 hours. In some experiments polymyxin B (P) was used at 10 µg/ml. Data are mean±SEM (N = 4 per group). * P<0.01 versus control, † P<0.001 versus control, ‡P<0.001 versus LPS.</p

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