Figure 5

Abstract

<p>A–C: Co-localization of fluorescein labeled Aβ40 (F-Aβ40) and Alexa Fluor® 633 labeled transferrin (AF633-Trf) in PC12 cells following: (A) 15 min; (B) 45 min; and (C) 60 min incubation. White masked areas indicate the extent of co-localization of F-Aβ40 and AF633-Trf. D: Cellular internalization of F-Aβ40 and AF633-Trf established by the XY, XZ, and YZ projections of differentiated PC12 cells treated with the fluorophores for 60 min. Optical sections (planes 1–45) were obtained from the coverslip bottom to the cell surface with a 0.6 µm Z-step interval.</p