Effect of H<sub>2</sub>O<sub>2</sub> on hypoosmotic medium induced amino acid release in the cortex.
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Abstract
<p>(a–c) Two microdialysis probes implanted on opposite sides of the cortex were perfused with hypoosmotic medium in the presence or absence of 1 mM H<sub>2</sub>O<sub>2</sub> given 20 minutes prior to and during one-hour hypoosmotic medium perfusion. The data represent the average dialysate levels ±SEM of glutamate (a), aspartate (b) and taurine (c) from 9 rats. ** p<0.01 HYPO vs. HYPO+H<sub>2</sub>O<sub>2</sub>. In separate experiments, rats were perfused with 1 mM H<sub>2</sub>O<sub>2</sub> alone (N = 5).</p