Activity of a Hypothetical LexA-Regulated Promoter, Parameterized as ∝1/(1+(<i>LexA</i>/100<i>nM</i>))
- Publication date
- Publisher
Abstract
<p>The blue curve is for default parameters with UV dose 20 J/m<sup>2</sup>. The position of the second peak coincides with the generation of Pol V and is due to the feedback between Pol V and RecA* levels, mediated by Pol V–assisted bypass of replication forks. The red curve is produced by averaging more than 200 runs of the model, each with a different value for the number of replication forks, <i>N<sub>f</sub>,</i> uniformly distributed between 1 and 3 (<i>N<sub>f</sub></i> = 2 for the blue curve).</p
