Multi-Cilia Cells Start to Differentiate as a Result of Jagged2a-Notch Signaling from 17 ss Onwards

Abstract

<div><p>(A–C) <i>rfx2</i> expression in (A) wt embryos, (B) <i>mib<sup>ta52b</sup></i> mutants, and (C) <i>jagged2a-sp</i> morphants at 15 ss.</p><p>(D–F) <i>rfx2</i> expression in (D) wt embryos, (E) <i>mib<sup>ta52b</sup></i> mutants, and (F) <i>jagged2a-sp</i> morphants at 18 ss.</p><p>Arrows point to the <i>rfx2</i> expression in the (A–C) IM and (D–F) pronephric duct. <i>rfx2</i> staining in the neural tube (arrowheads) indicates the neurogenic phenotype in (B and E) <i>mib<sup>ta52b</sup></i> mutants compared to that of (A and D) wt embryos.</p><p>All embryos, anterior to the left. (A–C) are dorsal views; (D–F) are lateral views. Bar scale: 200 μm (A–C) and 100 μm (D–F).</p></div

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