Changes in cytokine levels during TB treatment.


<p>IFNγ, IP-10, MIG and MCP-1 levels were measured in infected (left hand panels, A, C, E, G) and non-infected (right hand panels, B, D, F, H) mice before (black squares) and after 3, 7, and 21 days of treatment with RIF+INH (open circles) or placebo (black circles). In the infected groups within 7–21 days of treatment with RIF+INH levels of all 4 cytokines were lower compared to placebo treated mice. In the non-infected mice no differences in levels were seen between different treatments or time points. * p<0.05, ** p<0.01, *** p<0.001</p

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