MDS-MSC inhibit the endocytosis of monocyte derived DCs.

Abstract

<p>DCs <b>(5×10⁵)</b> were incubated in medium with FITC-labeled dextran at a concentration of 1 mg/ml in the presence of MSC <b>(5×10⁴)</b> at day 7. After an incubation period of 60 min at 37°C (green line) or 4°C as a control (gray line), cells were harvested and analyzed by FACS.Numbers in histograms indicate the mean fluorescence of each cell population. Results are expressed as mean±SD of triplicates of 5 separate experiments. *P≤0.05.</p