Pharmacokinetic parameters of paclitaxel/17-AAG-loaded micelles in comparison with those of the free drugs in tumor-bearing mice (mean ± SD, n = 4).

Abstract

<p>Abbreviations:</p><p>t<sub>1/2</sub>: elimination half-life; AUC: area under the plasma drug concentration versus time curve; CL<sub>T</sub>: total clearance; V<sub>D,SS</sub>: apparent volume of distribution at the steady-state.</p

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