Pooled measures on the relationship of eNOS gene 4b/a, T-786C and G894T polymorphism with ischemic stroke.

Abstract

<p>DHWE: deviated from Hardy–Weinberg equilibrium in controls.</p>a<p>Two articles (Kim et al. Meng et al.) in 4b/a and T-786C and one article (Di et al.) in G894T for recessive model were not sufficient to calculated pooled OR.</p>b<p>One article (Meng et al.) in 4b/a and T-786C and one article (Di et al.) in G894T for recessive model were not sufficient to calculated pooled OR.</p>c<p>p-values was for observed pooled odds ratios. when I²≤50%, it was for FEM, otherwise it was for REM.</p>*<p>Pooled ORs were not calculated for only two articles left sufficient to calculate pooled ORs after excluding articles with OR>3.0.</p><p>FEM, fixed effect model; REM, random effect model</p><p>Dominant model: aa + ba vs. bb for 4b/a, CC + TC vs. TT for T-786C, and TT + GT vs. GG for G894T.</p><p>Recessive model: aa vs. ba + bb for 4b/a, CC vs. TC + TT for T-786C, and TT vs. GT + GG for G894T.</p><p>Codominant model: a vs. b for 4b/a, C vs. T for T-786C, and for T vs. G for G894T.</p