Relationship between X inactivation rule and parent-of-origin dominance coefficients (<b><i>h<sub>mat</sub></i></b><b>, </b><b><i>h<sub>pat</sub></i></b><b>; see </b><b>Table 1</b><b>).</b>
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Abstract
<p>Results are based on the power function for female fitness, <i>w</i>(<i>x</i>) = 1−<i>x<sup>k</sup>s<sub>f</sub></i>, where <i>x</i> represents the proportion of female cells expressing the <i>A</i><sub>1</sub> allele, <i>s<sub>f</sub></i> is the haploid or homozygous selection coefficient, <i>h</i> is the degree of masking (equivalent to a dominance coefficient of <i>A</i><sub>1</sub>) in individuals practicing unbiased RXI (<i>ξ</i><sub>11</sub> = ½), and <i>k</i> = −ln(2)/ln(<i>h</i>). For additional details, see the main text. The figure is modified from, and inspired by, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003440#pgen-1003440-g001" target="_blank">Figure 1a</a> of <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003440#pgen.1003440-Guillaume1" target="_blank">[50]</a>.</p