Sex-differential selection favors the evolution of biased RXI.

Abstract

<p>Black curves are based on <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003440#pgen.1003440.e017" target="_blank">eq. (8)</a> for the mutation-selection balance model of genetic variation; diamonds are based on numerical evaluation of the more exact <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003440#pgen.1003440.e011" target="_blank">eq. (7)</a>. Gray curves are based on <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003440#pgen.1003440.e018" target="_blank">eq. (9)</a> for sexually antagonistic alleles maintained by balancing selection. Results for the mutation-selection balance case assume equal male and female selection coefficients (<i>s_m</i> = <i>s_f</i>). Biases are further accentuated when <i>s_m</i>><i>s_f</i>; biases may be dampened or reversed when <i>s_m</i><<i>s_f</i>.</p