The overexpression of Cry1 mRNA and protein in colorectal cancer tissues.

Abstract

<p>(<b>A</b>) A representative image of Cry1 staining in colorectal cancer tissues is shown. (<b>B</b>) A representative image of Cry1 staining in adjacent noncancerous tissues is shown. (<b>C</b>) Cry1 protein expression level was higher in tumor tissues compared to adjacent control tissue as detected by immunoblotting (mean±SEM; n = 109; * **, <i>P</i><0.001). (<b>D</b>) Average T/N ratios of Cry1 mRNA expression in paired colorectal cancer (T) and normalmucosa tissues (N) were quantified by qPCR and normalized to GAPDH. Error bars represent the standard deviation of the mean (SD) calculated from three parallel experiments. Magnification is ×200.</p