Movement of intracellular part of TM7 in agonist-bound receptor structure.

Abstract

<p>(A) The superimposed initial (grey) and final (yellow) agonist-bound structures. (B) Plot of the kink angle in TM7 with a pivot point at P308^7.50 for both simulations with agonist. During the simulation TM7 is gradually bending and the kink angle is changing from 155° to 130°.</p