<p>α-synuclein alone aggregates to fibrils that form bundles. When aggregation takes place in the presence of lipid vesicles (L/P = 1), fibrillar co-aggregates composed of protein and lipids form. These aggregates arrange into mesh-like tangles. At higher L/P ratios, the excess lipid vesicles adsorb to the fibrils, and due to strong interaction with the surface, the vesicles are deformed to non-spherical shape.</p
