Assessment of oxidative stress and antioxidative capacity.

Abstract

<p>Changes in general reactive oxygen species (ROS) levels and malondialdehyde (MDA) generation, a final degradation product of lipid peroxidation, are shown in (<b>A</b>) and superoxide dismutase (SOD) and reduced glutathione (GSH) in (<b>B</b>). <b>§</b>: <i>P</i><0.01 compared with SHO group (sham operation), <b></b>: <i>P</i><0.01 compared with UUO group (model group subjected to unilateral ureteral obstruction), <b>☆</b>: <i>P</i>>0.05 compared with UUO group. PHB⁻: UUO rats treated with lentivirus carrying siRNA PHB; PHB⁺; UUO rats treated with lentivirus carrying PHB; Negative control: UUO rats treated with control viruses; AOX: antioxidant.</p