The infarct size is smaller in E2F2 KO mice and larger in endothelial specific E2F3 KO mice than in their WT littermates.

Abstract

<p>Masson Trichrome staining was performed in heart samples 28 days after MI surgery. (<b>A</b>) Representative microphotographs and (<b>B</b>) Quantification of the infarct size. n = 12 mice per group; *P<0.05 versus VE-Cre; E2F3^+/+, ^#P<0.05 versus E2F2 WT; Scale bar = 100 µm.</p