Poly I:C upregulates expression of CXCR3 ligands in submandibular glands in an IL-7-dependent fashion

Abstract

<p>C57BL/6 mice were pre-treated with anti-IL-7Rα 2 hours prior to poly I:C injection. (A) Levels of CXCL9, 10, 11 and CXCR3 mRNA were measured from submandibular glands 24 hours after poly I:C administration, presented relative to that of β-actin. (B) Submandibular gland sections stained with CXCL9 and DRAQ5. All data are the average of or representative of 6 individual mice (2 mice per experiment, total 3 independent experiments).</p

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