Biochemical disruption of EWS-FLI1 and p53 binding to DNA.
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Abstract
<p>Dose response for disruption of recombinant EWS-FLI1 (red lines) and p53 (black lines) binding to DNA in the presence of indicated compounds was measured using AlphaScreen proximity assays. Data plotted as mean +/β SD of triplicate samples and are representative of 2 independent experiments.</p